In a campaign dogged by injuries, Klopp sought to address his long-standing issues at the back with the signings of Ozan Kabak and Ben Davies on deadline day, while a matchday regular, Takumi Minamino, left on loan.
Neither Kabak nor Davies start tonight, however, with the manager making two alterations from Sunday’s win at the London Stadium.
Davies makes the bench but Kabak’s arrival came too late, with youngster Jake Cain also included among Klopp’s substitutes.
Liverpool: Kelleher, Alexander-Arnold, Phillips, Henderson, Robertson, Wijnaldum, Thiago, Milner, Shaqiri, Salah, Firmino
Substitutes: Adrian, Davies, R.Williams, N.Williams, Tsimikas, Cain, Jones, Oxlade-Chamberlain, Origi
Brighton: Sanchez; White, Webster, Dunk; March, Bissouma, Alzate, Burn; Gross, Trossard, Maupay
Substitutes: Walton, McGill, Karbownik, Connolly, Lallana, Moder, Tau, Zeqiri, Weir