Two Italians have been charged following an assault on 53-year-old Sean Cox, who is in a critical condition, ahead of the first leg at Anfield this week and a delegation from the club met officials from UEFA, police and the Serie A club in the Italian capital on Friday to discuss their issues.
Klopp admits he is still shocked by what happened on Tuesday but hopes there will be no repeat next week.
“As you can imagine all our thoughts and prayers at this moment are with Sean and his family,” said the Reds boss, who at his pre-match press conference wore a Liverbird badge in the colours of the Irish tricolour in support of Cox and his family.
“I think the game on Tuesday showed the beauty of the game during the game and showed it’s most ugly face of parts of the game before the game.
“When I first heard of it I cannot describe my emotions in English. It should never have happened, it should never have happened before and it should not happen in the future and we all have to do everything to make sure things like that will not happen any more.
“I obviously don’t have the solution for it, probably no-one has that, but it is unbelievable that something like this can happen.”
On fan behaviour and the suggestion there could be more trouble involving Liverpool supporters, Klopp said: “Since I’ve been here I’ve never heard anything about that. I can’t remember anything like that.
“Of course it is difficult to police but the police, as I understand, will do the job.
“It is common sense. What can I say which they don’t already know and if I say it would that change it?
“It is easy to say: behave like how you want to be treated yourself. If you are in the street you want to be safe, that’s how it is.”
Worries over the safety of fans next week dominated preparations for Saturday’s visit of Stoke.
Klopp has a number of injury worries with only three fit senior midfielders after Alex Oxlade-Chamberlain’s season was ended by a knee ligament problem sustained in the 5-2 win over Roma.
“I have no words for that,” said Klopp.
“I cannot believe that this wonderful player, person, in such a positive situation, helping the team, having a clear, clear challenge, something like this happens.
“It’s just a shame, it’s not fair, to be honest.
“I told him we will wait for him like a good wife when a man is in prison.”
Klopp also has a concern over Sadio Mane, who was pictured visiting a private hospital in the city on Thursday.
“He was only visiting a friend,” he joked.
“Of course there is something. We will see.
“It is not that serious; there is a chance for tomorrow. If we use that chance or not… it is quite early in the day.
“In these times, you always have to use each second and minute, speak to the player, speak to the doctor, speak to the physiotherapists and all that stuff.
“At the end, you have to make a decision and I will make a decision.”