Klopp’s team has been changed up of late as the manager juggled his resources for a heavy league programme last week, and the win over Napoli in midweek in the Champions League.
Four wins in succession put the Reds right in form heading into this crunch clash at Anfield—and the strong lineup reflects the importance of the match.
Alisson remains in goal and the majority of the back line picks itself ahead of him.
On the right is where Klopp had a decision to make and Nathaniel Clyne comes in for his first league appearance of the season.
United have gone with a defensive outlook in the centre of the park, while Juan Mata, Paul Pogba and Anthony Martial are all on the bench.
Substitutes: Mignolet, Henderson, Sturridge, Moreno, Lallana, Shaqiri, Camacho.
Man United: De Gea; Dalot, Smalling, Lindelof, Darmian; Herrera, Matic; Rashford, Lingard, Young; Lukaku.
Substitutes: Romero, Bailly, Valencia, Fellaini, Mata, Pogba, Martial.