The Reds take to the Stadion Ljudski vrt for their third game since returning to Europe’s top tier, facing off against Slovenian PrvaLiga champions Maribor.
After disappointing draws with both Sevilla and Spartak Moscow, and Saturday’s 0-0 draw with Man United, Klopp’s side need a morale-boosting win in midweek.
Klopp could shuffle his pack for a relatively easy tie, with Maribor ranked 77th in Europe, which could provide chances for a host of fringe figures.
Three of those came off the substitutes’ bench at Anfield on Saturday, with Oxlade-Chamberlain bright in his cameo role on the right wing.
Liverpool currently sit second in Group E in the Champions League, two points behind leaders Spartak, while Maribor are fourth, having taken one point so far.
Liverpool Squad in Maribor
Goalkeepers: Mignolet, Karius, Ward
Defenders: Matip, Lovren, Klavan, Gomez, Alexander-Arnold, Moreno, Robertson
Midfielders: Henderson, Can, Wijnaldum, Oxlade-Chamberlain, Milner, Grujic
Forwards: Firmino, Coutinho, Salah, Sturridge, Solanke