The two sides will meet at the Macron Stadium with a 7:45pm kick-off after playing out a goalless draw at Anfield on Saturday evening.
The replay will be shown live on BBC One, with coverage starting at 7:30pm.
With the Merseyside derby the following Saturday, Liverpool would probably have preferred the match to have taken place on the Tuesday instead.
It could see Daniel Sturridge‘s first start since returning from injury, against the side he enjoyed a good loan spell with earlier in his career.
Let us know what you think to Liverpool‘s chances of progressing against in-form Bolton and who you’d like to see the Reds face in the fifth round if they do in the comments below.
1. Crystal Palace
2. Cambridge United or Manchester United
3. Blackburn Rovers
4. Bradford City
5. Derby County
6. Preston North End or Sheffield United
7. West Bromwich Albion
8. Aston Villa
10. Liverpool or Bolton
11. Leicester City
13. Rochdale or Stoke City
14. Sunderland or Fulham
15. West Ham