Four Liverpool players have been included in England manager Gareth Southgate’s squad to take on Scotland and Spain this month.
The Three Lions first take on Scotland (November 11) in a World Cup qualifier, before a high-profile friendly against Spain (November 15).
The quartet were all set to be included in Southgate’s first squad for the October break, but both Clyne and Lallana pulled out of contention through injury.
However, they are now set to turn out for their national team at Wembley, depriving Klopp of some of his key players for crucial training time at Melwood.
With Henderson and Lallana also key starters, and Sturridge an invaluable option from the substitutes’ bench, Klopp will be hoping for no injury setbacks on duty.
The 49-year-old is already facing a season without Danny Ings, with the striker ruled out for up to nine months following a knee injury.
Ings was on the fringes of the England squad two years ago, but injuries have hampered his progress for both club and country.
England’s last clash with Scotland came in the November international break in 2014, with a goal from Alex Oxlade Chamberlain and a brace from Wayne Rooney sealing a 3-1 victory.
Meanwhile, the last time the Three Lions played Spain saw Mario and Santi Cazorla consign Roy Hodgson’s side to a 2-0 loss.
Midfielders: Dier (Tottenham), Drinkwater (Leicester), Henderson (Liverpool), Wilshere (Bournemouth), Lallana (Liverpool), Lingard (Man Utd), Rooney (Man Utd), Sterling (Man City), Townsend (Crystal Palace)