The Reds take on their top-four rivals at Anfield, hoping to arrest the miserable form they’ve shown since the turn of the year.
Having lost of their first 10 games in 2017, Liverpool need to turn things around quickly if they are to secure Champions League football for next season, and victory over Spurs is crucial.
Preparing his side to take on Mauricio Pochettino’s strong north London outfit, Klopp made just one change to his previous lineup away to Hull City.
Jordan Henderson continues in his place in the No. 6 role.
The Reds captain is flanked by Wijnaldum and Adam Lallana, as Klopp sticks with his 4-3-3 formation.
Spurs are unbeaten in their last 11 games in all competitions, winning nine of those, and present a big challenge for Liverpool at Anfield.
But Klopp will be desperate to ensure his side respond to last weekend’s loss away to Hull with a victory, and re-establish themselves as a contender at the top end of the table.
Liverpool: Mignolet; Clyne, Matip, Lucas, Milner; Henderson, Lallana, Wijnaldum; Mane, Coutinho, Firmino
Substitutes: Karius, Klavan, Moreno, Alexander-Arnold, Can, Sturridge, Origi
Tottenham Hotspur: Lloris; Walker, Alderweireld, Dier, Davies; Dembele, Wanyama; Eriksen, Alli, Son; Kane
Substitutes: Vorm, Trippier, Wimmer, Winks, Sissoko, Nkoudou, Janssen