The Reds take to the Etihad Stadium looking to do the double over top-four rivals City and establish themselves as favourites to secure Champions League football next season.
Having already taken three points from Pep Guardiola’s side on New Year’s Eve, the Reds will be confident of sealing another victory away from home.
Klopp had further concerns over the fitness of Firmino and Divock Origi in the buildup, but the former has recovered to start, with the latter on the bench.
With five goals and an assist in his previous six outings against City, Coutinho will be key to Liverpool’s game plan at the Etihad, as Klopp looks to propel his side up the table.
Liverpool: Mignolet; Clyne, Matip, Klavan, Milner; Can, Lallana, Wijnaldum; Mane, Coutinho, Firmino
Substitutes: Karius, Lovren, Lucas, Moreno, Alexander-Arnold, Woodburn, Origi
Man City: Caballero; Fernandinho, Stones, Otamendi, Clichy; Toure; Sane, De Bruyne, Silva, Sterling; Aguero
Substitutes: Bravo, Sagna, Kolarov, Fernando, A. Garcia, Nolito, Iheanacho