The Reds welcome their city rivals across Stanley Park as they look to extend their unbeaten run to 10 games.
Following an emphatic 7-0 win over Spartak Moscow on Wednesday night, sealing their place in the Champions League‘s last 16, Liverpool will be in jubilant spirits heading into the derby.
And once again showcasing the depth at his disposal, Klopp has rung the changes for the fifth consecutive game, in search of a fourth win in a row.
The Reds have won their last three clashes with Everton, and have not lost in the Merseyside derby since 2010, winning seven and drawing seven of their 14 meetings since that 2-0 loss.
They’ve not lost at Anfield in the derby since 1999, going 18 games without defeat, and Klopp will be eager to extend that run.
Liverpool: Mignolet; Gomez, Lovren, Klavan, Robertson; Henderson, Milner, Oxlade-Chamberlain; Salah, Mane, Solanke
Substitutes: Karius, Alexander-Arnold, Can, Wijnaldum, Coutinho, Firmino, Ings
Everton: Pickford; Kenny, Holgate, Williams, Martina; Gueye; Sigurdsson, Davies, Rooney, Calvert-Lewin; Niasse
Substitutes: Joel, Keane, Jagielka, Schneiderlin, Lennon, Lookman, Vlasic