The Reds take to the Estadio do Dragao looking to secure a vital win on their first knockout-stage clash in Europe’s top tier since 2009.
Having got back to winning ways away to Southampton on Sunday, Klopp’s side can hope to extend their unbeaten run to four games and secure an aggregate lead before the return leg at Anfield.
So how should Klopp line his Liverpool side up in Portugal?
- Emre Can is ruled out due to suspension
- Jordan Henderson will return to the side as the No. 6
- Mohamed Salah & Roberto Firmino to provide the firepower
- Loris Karius confirmed to continue in goal
- Joe Gomez could return at right-back
- Dejan Lovren, Alberto Moreno, James Milner & Adam Lallana among the options to rotate
The Reds’ XI vs. Porto
Can’s absence can be considered a blow given the German’s recent form, but Klopp has already catered for the problem by resting Henderson at the weekend.
The captain will take over in the No. 6 role, in what could be one of few changes on Wednesday.
The only point of contention at the back is whether Lovren or Joel Matip partners Van Dijk, but with the former also rested on Sunday it could be that he comes back into the fold.
There is cause to suggest Sadio Mane requires a spell out of the side, but given the Reds are not in action again until February 24 and this is a must-win clash, the Senegalese will likely keep his place.
Mane, Salah and Firmino could spearhead the charge in a strong, settled XI:
However, given the strength of Klopp’s squad there are options for the German to rotate further, injecting energy into a side who played just three days previous.
The possible return of Gomez could see the 20-year-old replace Alexander-Arnold at right-back, while Moreno is fit and able to alternate with Robertson.
Furthermore, if Matip and Van Dijk are Klopp’s long-term duo at the back, this may be the opportunity needed to give the pair consecutive games together.
If Klopp recognises Mane’s struggles it could have an impact on the Reds’ midfield selection, as with Oxlade-Chamberlain brought off at St Mary’s the versatile ex-Arsenal man could be poised for a forward berth.
Oxlade-Chamberlain would provide a capable replacement for the off-colour Mane next to Salah and Firmino, and Milner could step in and take his place in the middle of the park.
This would leave a similarly impressive, but less likely, setup:
Liverpool are widely considered an outside bet for a lengthy Champions League run, and they can make a major statement with victory over an in-form Porto on Wednesday night.
Klopp certainly has the depth to ensure Sunday’s momentum is retained and built upon with the inclusion of some fresh faces.