The Reds welcomed the Blades to Merseyside on Thursday night, looking to carry on their remarkable Premier League form this season.
The Japan international may be required straight away, with Naby Keita unfortunately picking up an injury in the warmup.
Liverpool made the perfect start, thanks to Mohamed Salah‘s 14th goal of the campaign.
Andy Robertson profited from a slip by George Baldock, squaring the ball for the Egyptian King to fire home in front of the Anfield Road end.
Jordan Henderson was outstanding in the middle of the park throughout, as he carries on his superb run of form.
Sadio Mane got it on the act after the interval, scoring at the second attempt after a beautiful one-two with Salah to cap a stunning counter-attack.
Klopp and Henderson were along those who saluted the crowd after the final whistle, on a night when Liverpool were truly excellent.