Bridge-Wilkinson has taken the role after Barry Lewtas stepped up the take charge of the under-23s, with the former Port Vale, Bradford and Carlisle midfielder promoted from the under-16s.
United serve as the first competitive opposition for a new-look U18s side, too, with the Premier League confirming the full fixture list for 2020/21 on Monday afternoon.
Liverpool head to United on Saturday, September 12, giving their first-year scholars an early chance to impress.
Melkamu Frauendorf and Mateusz Musialowski are both new signings, and have already caught the eye with goals over the summer, as they make a strong first impression at Kirkby.
Tom Hill looks set to captain the young Reds into the new season, and he could be joined by the likes of Layton Stewart, Tyler Morton, Jakub Ojrzynski, James Balagizi and Conor Bradley in a talented young side.
The U18s will host last season’s champions Man City on Saturday, September 26, while their first Merseyside derby is an away trip on Saturday, October 24 and the season ends at home to Derby on Saturday, May 1.
Liverpool U18s Fixtures, 2020/21
Saturday 12 – Middlesbrough (A)
Saturday 19 – Derby (A)
Saturday 1 – Derby (H)