In a season where games come nearly every three days, it is far from an ideal situation and the Reds will now turn to two teenagers and Nat Phillips for a natural centre-back.
Rhys Williams and Billy Koumetio round off the options Klopp has available to him, but he has not ruled out looking for an alternative solution.
The boss cited the success of ex-Red Javier Mascherano as an example of not necessarily needing a particular height advantage to excel in the position.
“They’re all good in training,” Klopp said of his young centre-back options as he opened up on the options available to him.
“I know Nat the longest so I was really happy with his development since I’ve known him.
“He’s made big, big steps and is an exceptional character and the little problem was that we were all convinced how it looked that he [would leave].
“There were a lot of clubs interested in him and in the end, maybe because of the coronavirus crisis, no one had the money to do it.
“But we expected him to leave the club, to be honest. Thank god he didn’t! But that’s the only reason why he isn’t in the Champions League squad.
“And we still, obviously, have other options like Hendo, or Gini or James [Milner] and Robbo can play centre-half as well – they are all not smaller than Mascherano, for example, and he played pretty well in that position.
“We have one or two options and one of them we will choose, which one you have to switch on the television tomorrow night [to see].”
Mascherano was, of course, one of the first players to challenge the way one looked at a centre-back – with efficiency on the ball and playing out from the back key to his game.
And the four options Klopp namechecked are proficient in that area, with both Wijnaldum and Henderson having already featured in the heart of defence under his tutelage.
It is clearly something the manager has pondered and having admitted he gets “excited” about finding a solution to problems, it would not come as a surprise to see any of the aforementioned names at centre-back this season.