The Reds are facing a difficult return to action later this month with four of their players travelling to red-listed countries for international fixtures.
Alisson and Fabinho will travel to three, with Brazil visiting Venezuela and Colombia before hosting Uruguay, while Mane’s Senegal will play the second of their World Cup qualifiers against Namibia in South Africa.
Greece take on red-listed Georgia in the first of their games this month, before another away clash with Sweden.
The UK government have allowed exemptions for footballers returning from countries on the red list, but players are still required to quarantine for 10 days, only leaving once per day to train or play.
And while Mane and Tsimikas should be permitted to leave quarantine for the visit to Vicarage Road, they, like their Brazilian team-mates, are major doubts for the trip to Atletico Madrid on October 19.
There is, as it stands, a lack of clarity over whether players would be granted exemptions for overseas travel to games, but it seems highly unlikely.
Here is when the 10-day quarantine will begin and end for each of the four players at the earliest:
Alisson: October 16 to 26
- Fabinho: October 16 to 26
- Kostas Tsimikas: October 13 to 23
- Sadio Mane: October 13 to 23
Liverpool could feasibly arrange a workaround in all four players travelling directly to a training camp in Spain upon the conclusion of their international duties, however, with the club utilising bases in La Manga and Marbella in previous years.
One or more of Jurgen Klopp‘s fitness coaches could be stationed in Spain to oversee sessions, with head of fitness and conditioning Andreas Kornmayer working with Virgil van Dijk, Joe Gomez, Alex Oxlade-Chamberlain and Marcelo Pitaluga over the summer.
Whether this is in the club’s plans remains to be seen, but it could provide a quick fix – and though quarantine should then be required upon their belated return to the UK, they would still avoid missing further games.