The Reds travel to East Sussex just three days after their second group game in Europe, with Klopp make nine changes to his starting lineup on Thursday night.
Klopp’s plan paid off, belatedly, as after a host of chances of Salah and Nunez, Ryan Gravenberch made it 1-0 before the break.
Salah, Nunez and Wataru Endo were brought off at half-time, with Klopp confirming in his post-match press conference that “all three subs were planned.”
“If we can do it, I think we should try it,” he said of his planned substitutions.
“We have a really short time now, turnaround, for Brighton. Obviously last year we were awful there, so we have to do better.
“It’s difficult. I hate thinking about the game after the game [we’re preparing for], but in these quick turnarounds, sometimes we have to.
“We have the problem, two of our strikers not available for the next game, so we have to do it slightly differently.
“Tonight it went alright, worked out.”
Along with Salah, Nunez and Endo at half-time, Alexander-Arnold came off with 79 minutes played in his first start since a hamstring injury.
Gravenberch for Szoboszlai was the other alteration late on, though the Dutchman seemingly won’t be starting at the AMEX.