Liverpool have seen 18 players from their senior squad called up for international duty in November, though 10 others miss out – including those injured.
The Reds signed off before the final international break of the year with a 3-0 victory over Brentford at Anfield.
Before the trip to the Etihad, though, will be various qualifiers and friendlies around the world, with 18 first-team players called up.
Joining the long-haul journey is Luis Diaz, who returns to Colombia for the first time since the emotional rescue of his parents from kidnappers.
Closer to home, Trent Alexander-Arnold is the only Liverpool player in the England squad, while Dominik Szoboszlai (Hungary), Diogo Jota (Portugal) and Kostas Tsimikas (Greece) also have games in Europe.
Marcelo Pitaluga joins the Brazil U23s for the first time, Owen Beck and Tom Hill are with the Wales U21s, Kieran Morrison is part of the Northern Ireland U19s and Trent Kone-Doherty the Republic of Ireland U19s.
Liverpool also have young striker Keyrol Figueroa representing the United States at the U17 World Cup in Indonesia, with another four players at the U16s Victory Shield.
Wales called up Prince Kobe Cisse and Jayden Allmark for that tournament, while Harry Moran is with the Northern Ireland group and Cameron Williams with Scotland.
The majority of the first-team players not on duty were unavailable due to injury, including the latest absentee Ibrahima Konate.
Liverpool’s internationals in November
Senior players: Alisson, Kelleher, Van Dijk, Quansah, Alexander-Arnold, Tsimikas, Endo, Mac Allister, Szoboszlai, Elliott, Salah, Nunez, Diaz, Jota, Gakpo, Doak
Youth and loanees: Pitaluga, Chambers, Scanlon, Beck, Morton, Hill, Morrison, Kone-Doherty, Figueroa
Left out: Adrian, Matip, Gomez, Bradley, Gravenberch
Injured: Konate, Robertson, Thiago, Bajcetic, Jones