The Reds face Ligue 1 opposition in the Europa League, with a place in the last 16 on offer if results in Group E go their way.
After a frustrating 1-1 draw with Luton on Sunday, Klopp has seen his squad reduced by injury and illness, with 23 players flying to Toulouse.
The fit-again Ben Doak comes in on the right, while Diaz makes his first start since the Merseyside derby on the left and following the news of his father’s safe release, and Cody Gakpo leads the line.
A feel-good story also sees Kaide Gordon return to the matchday squad after a 17-month injury nightmare, though do not expect to see him turned to having only made his first competitive start in 21 months on Tuesday.
Toulouse: Restes; Costa, Nicolaisen, Diarra; Desler, Sierro, Schmidt, Casseres, Suazo; Dallinga, Donnum
Substitutes: Dominguez, Lacombe, Cissoko, Cesar, Kamanzi, Mawissa, Begraoui, Magri, Bangre, Keben
Liverpool: Kelleher; Gomez, Matip, Quansah, Tsimikas; Endo, Elliott, Mac Allister; Doak, Diaz, Gakpo
Substitutes: Alisson, Mrozek, Konate, Alexander-Arnold, Chambers, Scanlon, McConnell, Szoboszlai, Gordon, Jota, Salah, Nunez