The Reds’ passage to the knockout stage as group winners is already secured ahead of this trip to Belgium, meaning they have little to play for.
As such, the German has every reason to name an unfamiliar starting XI to run out at Lotto Park.
In midfield, Wataru Endo should be ready to take on the anchor role after playing just 45 minutes at Crystal Palace, though his minutes will still need to be managed if he is to deputise for Alexis Mac Allister against Man United.
Ahead of the Japan captain, Harvey Elliott has largely featured off the bench of late, and so fatigue is no reason to leave him out of this one as he looks to keep up his fine form.
And alongside him, it would be interesting to see James McConnell get a rare opportunity to show what he is about having impressed in pre-season.
Up top, Cody Gakpo might be worth calling up for a 60-minute runout having been used sparingly in this busy recent run.
As such, while he might be more comfortable on the right, Kaide Gordon is unlikely to complain about being given the opportunity to shine on the opposite flank.
Potential Liverpool XI: Kelleher; Bradley, Gomez, Quansah, Chambers; Endo, Elliott, McConnell; Doak, Gordon, Gakpo