Jurgen Klopp names a strong XI, but is with only one recognised centre-back after Steven Caulker failed a fitness test after suffering with a back injury before the game to rule him out.
That means Lucas Leiva starts alongside Tiago Ilori in the Reds’ defence.
At full-back, Jon Flanagan and Brad Smith start.
Youngster Cameron Brannagan, who impressed in the original tie at Anfield, is ruled out through illness.
Goalkeeper Simon Mignolet retains his place despite yet another mistake in the match against Sunderland at the weekend. Recalled loanee Danny Ward is sub again. The keeper is the only player to keep his place from the 2-2 draw with Sunderland on Saturday.
Liverpool: Mignolet, Flanagan, Lucas, Ilori, Smith, Stewart, Chirivella, Teixeira, Coutinho, Ibe, Benteke.
Subs: Ward, Enrique, Milner, Henderson, Sturridge, Origi, Randall.
West Ham: Randolph, O’Brien, Reid, Ogbonna, Cresswell, Noble (c), Obiang, Antonio, Kouyate, Payet, Valencia.
Subs: Adrian, Carroll, Collins, Moses, Oxford, Cullen, Parfitt-Williams.
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