The Reds will be boosted by the return of Daniel Agger, who has been sidelined through injury over the last two months.
All being well, Fernando Torres should also make a return to the starting line-up after coming off the bench to score in the 2-0 victory over Fulham at Anfield.
Rafa Benitez has declared Xabi Alonso unfit, but Yossi Benayoun may recover in time, while Harry Kewell is pushing for a starting place.
More team news to follow. The match is live on Sky Sports One, kick off 12:45pm.