Daniel Sturridge, who played over 75 minutes for the first time since October on Sunday, isn’t risked from the start after suffering cramp during extra time. He’s not among the subs either.
Divock Origi instead starts up front.
Martin Skrtel is named on the bench after recovering from injury.
City boss Manuel Pellegrini makes three changes, with Pablo Zabaleta, Jesus Navas and Joe Hart replacing Sagna, Yaya Toure and Willy Caballero.
Liverpool: Mignolet, Clyne, Toure, Lovren, Flanagan, Henderson, Can, Milner, Lallana, Firmino, Origi.
Subs: Ward, Skrtel, Moreno, Allen, Ibe, Coutinho, Benteke.
Man City: Hart, Zabaleta, Clichy, Kompany, Otamendi, Fernando, Fernandinho, Navas, Silva, Sterling, Aguero.
Subs: Caballero, Sagna, Demichelis, Kolarov, Bony, Iheanacho, Mangala.