The Reds headed to north London for their final outing before Christmas, looking to bring their unbeaten run to 13 games.
After their 4-0 victory away to Bournemouth last time out, Klopp’s side can take to the Emirates Stadium confident of another three points against a side they thrashed at Anfield in August.
But the Gunners’ defeat at the start of the season provides Arsene Wenger with fuel to prompt a revival, ensuring Friday’s face-off is a challenging one.
And while he has continued his rotational approach midway through a congested 13-game run, Klopp has once again named a strong side.
Liverpool have not lost to Arsenal in their last five games, winning their three most recent meetings, and Klopp will be hoping for another vital three points at the Emirates.
Arsenal: Cech; Bellerin, Koscielny, Monreal, Maitland-Niles; Xhaka, Wilshere; Iwobi, Ozil, Sanchez; Lacazette
Substitutes: Ospina, Mustafi, Kolasinac, Coquelin, Elneny, Walcott, Welbeck
Liverpool: Mignolet, Gomez, Lovren, Klavan, Robertson; Henderson, Can, Coutinho; Salah, Mane, Firmino
Substitutes: Karius, Alexander-Arnold, Milner, Wijnaldum, Lallana, Oxlade-Chamberlain, Solanke