Thirty Liverpool players are set to depart for international duty in the October break, including 19 called up to represent their senior national teams.
The Reds ended a 23-day spell that saw them play seven games with a 0-0 draw at home to Man City on Sunday, and now head off for a 11-day break between domestic outings.
With their next clash coming at Huddersfield Town on October 20, the focus now turns to various qualifiers and friendlies on the international stage.
Jurgen Klopp will see the majority of his first-team squad leave Merseyside, with a host of loanees and academy players also involved.
Joe Gomez, Trent Alexander-Arnold and Jordan Henderson are in the England squad for their meetings with Croatia and Spain.
Croatia manager Zlatko Dalic has included Dejan Lovren in his selection for that UEFA Nations League tie in Rijeka.
Alisson, Fabinho and Roberto Firmino have all kept their places in the Brazil squad, while Virgil van Dijk and Georginio Wijnaldum will feature for the Netherlands.
Championship loan duo Ben Woodburn and Harry Wilson have been named in Ryan Giggs’ Wales squad, and Andy Robertson will captain Scotland against Israel and Portugal.
Sadio Mane, Mohamed Salah and Naby Keita are all in Africa Cup of Nations qualifier action for Senegal, Egypt and Guinea respectively.
Elsewhere, Xherdan Shaqiri can be expected to play a key role for Switzerland, as they take on Iceland and Simon Mignolet‘s Belgium.
Two academy talents have also received senior call-ups, with Liam Millar keeping his place in the Canada squad and Kai McKenzie-Lyle retained for Guyana.
On the youth international stage, Dominic Solanke is part of the England U21s squad and Kamil Grabara can hope to feature for the Poland U21s.
Isaac Christie-Davies (Wales U21s) and Corey Whelan (Republic of Ireland U21s) are also in action for the home nations, while Rafa Camacho has stepped up to the Portugal U20s.
Morgan Boyes and Neco Williams are both in the Wales U19s squad, Curtis Jones is with the England U18s and Vitezslav Jaros should start for the Czech Republic U18s.
Finally, Edvard Tagseth is again named in the Norway U18s squad, while youngster Owen Beck will join up with the Wales U17s again.
Liverpool in the October International Break
Senior players called up: Alisson, Mignolet, Grabara, Van Dijk, Gomez, Lovren, Alexander-Arnold, Robertson, Henderson, Wijnaldum, Keita, Fabinho, Woodburn (loan), Jones, Firmino, Salah, Mane, Shaqiri, Solanke, Wilson (loan), Camacho
Notable youth: McKenzie-Lyle, Jaros, Boyes, Whelan (loan), N.Williams, Beck, Tagseth, Christie-Davies, Millar
Left out: Kelleher (injured), Matip (retired), Moreno, Clyne, Lewis, Milner (retired), Lallana (injured), Oxlade-Chamberlain (injured), Markovic, Adekanye, Sturridge, Origi, Brewster (injured)