Salah has scored in Liverpool’s opening league game in each of his three seasons with the club.
He could be the first Reds player ever to do it for a fourth in a row and only the second Premier League player overall, matching Teddy Sheringham between 1992/93 and 1995/96.
They have never scored four or more in the first match of a league season in three successive years.
Newly Promoted Prowess
It will be the second successive season that Liverpool have met a newly promoted team in the first game of the league campaign, having beat Norwich here 4-1 last term.
They are unbeaten in last 28 home league games against newly promoted sides, winning 23 and drawing five. Klopp has won all 13 of his.
The Reds have not lost in their last seven opening fixtures of a campaign, with six wins and a draw since losing at West Brom in 2012.
Since losing to Blackpool in their first game back in the top flight in 1962, Liverpool have only once lost their opening-day fixture at Anfeld – to Chelsea in 2003 (2-1).
Of the others, Liverpool have won 22 with three draws.
Defending the Title
Klopp will hope to become only the second Liverpool manager to successfully defend the league title.
Of all Reds managers only Bob Paisley, who won back-to-back titles on three occasions, has successfully defended the trophy.
Liverpool last began a campaign as league champions in 1990, also facing Yorkshire opposition – winning 3-1 at Sheffield United.
This is Leeds’ first Premier League fixture for 5,964 days.
Their last game was on May 15, 2004, then they lost 1-0 at Chelsea on the final day.
They finished 19th that season and were relegated along with Leicester and Wolves, after appearing in each of the first 12 seasons of the Premier League.
During that campaign they fielded James Milner, Nick Barmby, Scott Carson, Dominic Matteo and Jermaine Pennant, all of whom have worn a Liverpool shirt.
Milner scored three league goals that season.
Milner’s Landmark Reunion
Milner has only faced Leeds twice in his career and never in the league.
The midfielder played 54 times for Leeds between 2002 and 2004, scoring five times. He has featured in all of Leeds’ last 30 Premier League games.
Today, he could play his 150th league game for Liverpool and could captain the club for the 50th time in the Premier League.
Michael Oliver took charge of Liverpool’s opening game of last season (vs. Norwich); it is his first game in charge of Leeds for four-and-a-half years.
Last Season’s Scorers
Liverpool: Salah 23, Mane 22, Firmino 12, Oxlade-Chamberlain 8, Origi 6, Wijnaldum 6, Van Dijk 5, own goals 5, Henderson 4, Milner 4, Alexander-Arnold 4, Keita 4, Jones 3, Robertson 3, Fabinho 2, Matip 2, Hoever 1, Lallana 1, Lovren 1, Shaqiri 1
Leeds: Bamford 16, Hernandez 9, Klich 7, Harrison 6, Alioski 5, Helder Costa 5, Dallas 5, Nketiah 5, Ayling 4, Roberts 4, own goals 3, Cooper 2, Phillips 2, Shackleton 2, Berardi 1, White 1
* Statistics courtesy of LFC statistician Ged Rea (@ged0407).