Salah was forced off after 30 minutes, with the score at 0-0, in Kyiv in 2018 after being hauled to the ground by the Spain defender which resulted in a shoulder injury.
The Reds went on to lose the final 3-1, although they returned 12 months later to lift a sixth European Cup in Madrid against Tottenham with Salah opening the scoring in the final.
As the two teams prepare to face each other next Tuesday in the Champions League quarter-finals, Salah said he was not dwelling on his history with Ramos.
“That game is in the past, so I don’t think about it. I’m thinking about the team. Everyone is focused on their team and everyone wants to win…that’s it,” the 28-year-old told Marca.
“What’s going to happen now isn’t going to change the result of the final in Kyiv. That’s in the past.
“Let’s just say that I have special motivation to win the tie and go through to the semi-finals.”
Salah accepts both teams have changed since 2018 and, while only two of Liverpool’s starting lineup in Ukraine have left the club, they will also be without the injured Virgil van Dijk and Jordan Henderson.
Cristiano Ronaldo has left Real for Juventus while Gareth Bale, who came off the bench to score two decisive goals with the score at 1-1, is on loan at Tottenham.
“It’s different,” Salah said.
“They’ve lost some great players, like Cristiano Ronaldo – the best in the club’s history, someone that scored so many goals.
“At the same time, they’ve signed Hazard. Eden’s been unlucky, he’s been injured…but it’s a different team.
“This team is in the quarter-finals, it has great players [and] although they’ve lost Ronaldo’s goals I can’t say which is better.