Roberto Firmino is among those to remain on Merseyside, however, with the striker omitted from Tite’s Brazil squad for their World Cup qualifiers against Venezuela, Colombia and Uruguay.
The government have now agreed an exemption for elite footballers, which still requires a period of self-isolation but allows players to leave quarantine once a day to train or play.
Chelsea manager Thomas Tuchel has shed light on the situation for many of the Brazil squad, due to their clash with Uruguay falling on the morning of October 15.
“This is the life of international breaks in 2021. Like it or not, what can I do?
“He’s our player and he arrives on the matchday back from a country where he then needs to do quarantine.
“Is this a good solution for us as a club? No, but we cannot hold him back. It’s impossible.
“If they call him, he needs to go, otherwise he gets suspended by FIFA. So there is no choice. You simply have to live with it.”
Though they are ruled out against Watford due to the logistics of travelling back from South America, the need for quarantine also almost certainly makes them unavailable against Atletico, too.
Despite players being granted permission to leave quarantine to play, this is unlikely to allow for the pair to fly to Spain and back during their 10-day period of isolation.
Meanwhile, there is no chance of the Brazilian FA agreeing to release their eight Premier League players before the Uruguay game, as it would leave Tite unable to name a full 18-man squad.
It would set a dangerous precedent, too, with Paris Saint-Germain, Juventus, Real Madrid, Benfica, Lyon, Marseille, Ajax and Basel also affected.
The Brazilian domestic schedule continues throughout the break, with Palmeiras, Atletico Mineiro, Flamengo and Internacional all due to be without their internationals for at least three games.