Alongside them, Ibrahima Konate should be ready to feature ahead of Joe Gomez, who may be needed at right-back late in the game, while Kostas Tsimikas was rested to come back in on the left of defence.
In midfield, with Alexis Mac Allister still out injured, Wataru Endo looks a likely starter in the holding role having also come through a first-half outing of his own in midweek.
And there is one certainty about who will feature ahead of him in the middle, with Dominik Szoboszlai rested against Union SG and ready to come back in.
His fellow No. 8 would typically be harder to guess, but Curtis Jones playing the entire 90 minutes on Thursday suggests it will be Ryan Gravenberch who gets the nod.
Up top, Mohamed Salah and Luis Diaz look obvious picks on either flank given the lack of alternatives and their absence against USG.
And while Cody Gakpo might have pushed Darwin Nunez for a start, the Dutchman was given the full game in Belgium and so will likely be used from the bench.
Predicted Liverpool XI vs. Man United:Alisson; Alexander-Arnold, Konate, Van Dijk, Tsimikas; Endo, Szoboszlai, Gravenberch; Salah, Diaz, Nunez