After two defeats in three opening fixtures, a win at the Reebok Stadium is required to get Liverpool back on track.
Huge questions have been raised following defeats to Spurs and Villa, but Bolton have troubles of their own.
Gary Megson’s side have lost 1-0 to both Sunderland and Hull and are without a goal this season. They face Tranmere in the Carling Cup on Tuesday night.
Liverpool will have new signing Sotirios Kyrgiakos available for the first time if required.
This fixture last season resulted in a comfortable 2-0 win for the Reds.
More match previews to follow.
Ruled out: Nabil El Zhar, Alberto Aquilani, Fabio Aurelio