The Reds take on Luis Enrique’s La Liga side in the penultimate outing of a busy pre-season, and the third of three clashes in the International Champions Cup.
With this providing the biggest test of his side’s credentials heading into 2016/17, Klopp has named a formidable starting lineup, including Philippe Coutinho, Roberto Firmino and Georginio Wijnaldum.
In midfield, Wijnaldum is joined by Emre Can, in what looks set to be a 4-2-3-1 formation.
Brannagan is set to seal a season-long loan move to Wigan Athletic in the coming days, with this outing likely his last for the Reds until next summer.
Liverpool: Mignolet; Clyne, Lovren, Klavan, Milner; Can, Wijnaldum, Lallana; Coutinho, Firmino, Mane
Substitutes: Manninger, Randall, Wisdom, Alexander-Arnold, Moreno, Matip, Stewart, Brannagan, Grujic, Henderson, Markovic, Origi, Ings
Barcelona: Ter Stegen; Vidal, Mascherano, Mathieu, Camara; Busquets, Arda, Denis; Messi, Munir, Suarez
Substitutes: Bravo, Masip, Douglas, Piqué, Rakitic, Iniesta, Mujica, Samper, Digne, S. Roberto, Alfaro, Vermaelen