The Reds welcome Mike Phelan’s side to Merseyside for their second Anfield outing of the season, looking to continue their fine league form.
Klopp has steered his side to three wins, one draw and one loss in their first five league games of 2016/17, as well as sealing victories over Burton Albion and, most recently, Derby County in the League Cup.
Eager to maintain this impressive streak, Klopp has named a strong starting lineup, making four changes from Tuesday night’s win over the Rams.
With Henderson serving as Klopp’s creative platform in the middle of the park, Adam Lallana and Georginio Wijnaldum return to their box-to-box roles, after sitting out on Tuesday night through minor injury.
Dejan Lovren misses out due to illness, leaving Lucas as Klopp’s backup centre-back.
Liverpool: Karius; Clyne, Matip, Klavan, Milner; Henderson, Lallana, Wijnaldum; Mane, Coutinho, Firmino
Substitutes: Mignolet, Lucas, Moreno, Grujic, Can, Origi, Sturridge
Hull City: Marshall; Elmohamady, Livermore, Davies, Robertson; Clucas, Huddlestone, Mason, Snodgrass; Hernandez, Diomande
Substitutes: Jakupovic, Maguire, Meyler, Maloney, Mbokani, Keane, Henriksen