But after his side went 1-0 down to a Jonathan Walters header in the first half, Jurgen Klopp opted to withdraw the duo.
Woodburn was particularly busy in attack, and was at the centre of a controversial penalty call waved away by referee Mike Dean, after the Welshman had turned Stoke left-back Erik Pieters.
Though their half-time substitution could have suggested some blame from Klopp, Matip does not believe this to be the case, with the Reds centre-back leaping to his young team-mates’ defence.
“There are 11 players on the field and you cannot say it’s their fault, it’s all [of] our fault, he explained.
“As a team we didn’t play well in the first half and then we tried to change something.
“They are still young and have a lot of talent. We will have a lot of fun with them.”
But after their victory over Stoke rounding off a stretch of three games in seven days, Liverpool have a week to prepare for their away clash with West Brom on April 16.
And Matip is relishing the extra time on the training field, with a successful top-four finish in sight.
“I think every team has this small injury list but we have to handle this,” he added.
“Now we have a week to concentrate and prepare for the next game, and I hope most of the team will be available.”
Klopp seems likely to persevere with his new system for the foreseeable future, and it could be that this affords both Alexander-Arnold and Woodburn more game time between now and May.
If this is the case, Matip is clearly confident they hold their own in the starting lineup.