Rafa Benitez’s side have secured second place courtesy of their superior goal difference over Chelsea.
The match sees two significant players take the spotlight – one on his way out of Anfield and one returning to the club.
Sami Hyypia will be hoping to be involved for a final time after ten years service at Anfield. The Finnish centre back has agreed a free transfer move to German outfit Bayer Leverkusen and The Kop will be sure to give the Liverpool legend the send-off he deserves.
Meanwhile, Spurs captain Robbie Keane returns to Anfield for the first time since his controversial departure in the winter transfer window. Ironically, Harry Redknapp’s side go into the game requiring a win to potentially secure a European spot – which would see them pay a further Â£1m for Keane’s transfer.
Pepe Reina will be seeking to keep another clean sheet, and in doing so record his fourth consecutive golden glove award.