Jamie Carragher starts for Liverpool, on his 34th birthday, and Andy Carroll is up front.
Maxi Rodriguez returns to the team, and Martin Kelly starts at right back. It looks like Carragher will play a holding midfield role in place of Charlie Adam.
Liverpool: Reina, Kelly, Agger, Skrtel, Enrique, Carragher, Henderson, Gerrard, Downing, Maxi, Carroll.
Subs: Johnson, Coates, Kuyt, Adam, Doni, Shelvey, Bellamy.
Man United: De Gea, Rafael, Smalling, Evans, Evra, Park, Carrick, Scholes, Giggs, Valencia, Welbeck.
Subs: Lindegaard, Ferdinand, Berbatov, Hernandez, Fabio, M Keane, Pogba.
Kick off at Anfield is 12:45pm, live on ITV1 (UK).