Christian Benteke is also named in a starting lineup that sees four changes from Thursday night’s 0-0 draw with to FC Sion in the Europa League.
Kolo Toure and Brad Smith make way for Skrtel and Moreno, as the German shuffles his pack.
With the three-man midfield of Henderson, Emre Can and James Milner proving effective against Sion, Klopp has persevered with the trio, with the captain making a first Premier League start under his new manager.
Preparing his side for a tough contest against Tony Pulis’ Baggies at Anfield, Klopp will look to exploit West Brom‘s weaknesses, with the physicality of Benteke and the creativity and guile of Coutinho likely key aspects of his selection.
Liverpool: Mignolet; Clyne, Skrtel, Lovren, Moreno; Henderson, Can, Milner; Lallana, Benteke, Coutinho
Substitutes: Bogdan, Toure, Firmino, Lucas, Allen, Origi, Ibe
West Brom: Myhill; Dawson, McAuley, Olsson, Evans; Brunt, Fletcher, Gardner; Morrison, McClean, Rondon
Substitutes: Lindegaard, Chester, Gnabry, McManaman, Berahino, Lambert, Anichebe
Liverpool vs. West Brom is not available on TV for UK viewers, stay with This is Anfield this afternoon for full coverage and reaction.