Lucas Leiva replaces Jordon Ibe in Klopp’s only change.
That means Christian Benteke continues on the bench and Roberto Firmino up front.
Visitors Man United are unchanged from the side that drew 3-3 with Newcastle in the week.
Liverpool vs. Man United kicks off at 2.05pm GMT.
Liverpool: Mignolet, Clyne, Toure, Sakho, Moreno, Lucas, Henderson, Can, Milner, Lallana, Firmino.
Subs: Ward, Caulker, Smith, Allen, Teixeira, Ibe, Benteke.
Man United: De Gea, Young, Smalling, Blind, Darmian, Schneiderlin, Fellaini, Lingard, Herrera, Martial, Rooney.
Subs: Romero, Borthwick-Jackson, McNair, Varela, Pereira, Mata, Memphis.
Ahead of the game, watch Klopp’s pre-match press conference: