The Reds take on Antonio’s Conte’s side at the Rose Bowl in Pasadena, kicking off at 4.35am (BST), but despite the challenge of their International Champions Cup opener, will be without a host of key names.
Having all joined Klopp’s squad late following summer breaks and transfers, the German has decided they are not ready for action, with Clyne a particular concern.
According to the Liverpool Echo‘s James Pearce, the right-back is suffering from a minor hamstring issue, and will sit out for a brief period.
However, while Sturridge is left out following his exploits with England at this summer’s European Championship, his Three Lions team-mates, James Milner, Jordan Henderson and Adam Lallana, are expected to feature against the Blues.
Milner and Henderson will vie with Kevin Stewart, Cameron Brannagan, Marko Grujic, Ovie Ejaria and Trent Alexander-Arnold for starting roles in midfield, though it remains to be seen whether late addition Emre Can will take part.
Possible Liverpool XI vs. Chelsea: Karius; Randall, Lovren, Klavan, Moreno; Stewart, Grujic, Ejaria; Mane, Firmino, Coutinho
Substitutes: Mignolet, George, Manninger, Wisdom, Alexander-Arnold, Brannagan, Can, Henderson, Milner, Lallana, Markovic, Ojo, Ings