The Reds take to the KC Stadium looking to return to top form in February, having rounded off a miserable January with a spirited 1-1 draw at home to Chelsea.
Taking on Marco Silva’s much-improved Hull, Liverpool still have a major task on their hands, but are buoyed by the return of some star names.
Lallana is also able to return in his impressive midfield role, joined by Emre Can to provide box-to-box support.
With Mane back from the Africa Cup of Nations and Coutinho reaching full fitness following an ankle injury, the wide duo both start alongside Firmino, who is primed to take up his regular centre-forward duty.
Hull City: Jakupovic; Elabdellaoui, Ranocchia, Maguire, Robertson; Huddlestone, Clucas, N’Diaye, Evandro; Grosicki, Hernandez
Substitutes: Marshall, Tymon, Meyler, Maloney, Niasse, Mbokani, Diomande
Liverpool: Mignolet; Clyne, Matip, Lucas, Milner; Henderson, Lallana, Can; Mane, Coutinho, Firmino
Substitutes: Karius, Gomez, Alexander-Arnold, Moreno, Wijnaldum, Sturridge, Origi