The pair missed the end of the 2016/17 campaign with foot and knee injuries respectively, depriving Jurgen Klopp of two of his key players.
As a result, Liverpool’s summer preparations are of vital importance, with the majority of Klopp’s squad set to reconvene at Melwood at the beginning of next month.
And according to the Telegraph, both Henderson and Mane will be fit to take part from the beginning of pre-season.
Neither have taken time off this summer, instead remaining on Merseyside to continue their rehabilitation.
Henderson opted to stay at Melwood in order to return to full fitness after a troubling issue that kept him out for over three months, while Mane was required to undergo further treatment after surgery.
But now able to join their team-mates on the training field, they can target a productive summer schedule.
One player who won’t be available from the start, however, is Danny Ings, who is still working his way back to fitness following a long-term knee injury.
The former Burnley striker, who has spent much of his Liverpool career on the sidelines, could link up with the first team at some stage in the summer, though.
Grujic should come back into the fold sooner than Can, though, with Serbia facing an early exit from the tournament in Poland having taken just one point from their first two Group B clashes.
The young midfielder is suspended for his nation’s final game against Spain on Friday, having picked up two yellow cards.
Those who represented their countries in World Cup qualifiers will also be provided further time off, with Klopp calling upon his non-internationals first.
Liverpool begin their pre-season fixtures away to Tranmere Rovers on July 12, before taking in trips to Hong Kong, Germany and Ireland.