The Reds reached the semi-finals of England’s least-cherished cup competition last season, and will be looking to improve on that this time around.
Standing in their way first is Craig Shakespeare’s Leicester, who subjected Klopp’s side to a 3-1 defeat at the King Power Stadium back in February.
Liverpool take on the Foxes at the same venue again on Saturday in the Premier League, and as a result both managers have shuffled their pack for Tuesday’s cup tie.
Danny Ward makes his first start of the season, and his first competitive appearance for the Reds since the end of the 2015/16 campaign, lining up between the sticks.
Both Solanke and Oxlade-Chamberlain will make their full debuts for the Reds after joining in the summer.
Leicester City: Hamer; Amartey, Dragovic, Morgan, Chilwell; Albrighton, Iborra, Ndidi, Gray; Slimani, Ulloa
Substitutes: Jakupovic, Benalouane, Choudhury, Mahrez, Musa, Okazaki, Iheanacho
Liverpool: Ward; Flanagan, Gomez, Klavan, Robertson; Henderson, Grujic, Wijnaldum; Oxlade-Chamberlain, Coutinho, Solanke
Substitutes: Karius, Moreno, Alexander-Arnold, Milner, Woodburn, Markovic, Ings