Karius was surprisingly selected instead of Simon Mignolet in the 4-0 win over Arsenal at the end of last month and reports last week emerged that the German would be the Reds’ stopper for European games – something Barcelona have done previously to good effect.
Mignolet returned to the starting XI against Man City on Saturday, with Klopp confirming that the Belgian is the Reds’ No.1 in goal.
In his pre-Sevilla press conference on Tuesday night, though, Klopp confirmed Karius would play in his side’s Champions League group stage opener at Anfield.
“If nothing happens tonight, Loris Karius will play tomorrow,” Klopp said.
Karius was not exactly convincing against Arsenal, almost being dispossessed with the ball at his feet more than once, so the pressure is on him to impress on Wednesday.
Meanwhile, Klopp explained that Mohamed Salah is expected to be fit despite missing training on Tuesday, but kept his cards close to his chest when asked if Philippe Coutinho may start against the Spaniards.