The Reds last took to the field a week-and-a-half ago, with that dramatic 4-3 win over Crystal Palace followed by a short warm-weather break in Dubai.
They were back at Melwood by the end of last week, with the focus remaining on success in the Premier League, as they still hold a four-point lead at the top of the table.
And Klopp believes Leicester, who have already secured victories over Chelsea and Man City this season, will be difficult opposition—despite having lost their last three games and four of the last five.
“We expect a very, very good side,” he told reporters.
“I’m really happy that it’s a Wednesday night game, because I hope that our supporters feel the need to [show] real support.
“It’s a while ago that we played at home, 10 days or so, so we are really looking forward to it, but it will not be easy as well, like the last game was not easy.
“But it’s all about squeezing everything out of the players, so we can really perform good enough to win.”
“Virgil was a little bit ill, but he trained yesterday so we will see” he said. “Dejan fine, Gini trained, Fabinho will train today.”
And the manager rejected claims City would now have an advantage in the title race as they play before Liverpool in eight of the next nine games, saying “you have to do your own work, your own job, if you want to have something.”
“You have to wait until tomorrow. We will play with a right-back, or a wing-back, [but] I don’t know [who],” he claimed.