The Reds are looking for their 13th win in 14 games in the Premier League this season, taking on the midtable Seagulls in a bid to maintain their eight-point lead at the top.
And while the Brazilian would have missed today’s game through suspension regardless, this now serves as the start of an extended period without one of Liverpool’s most important players.
With both Fabinho and Joel Matip on the long-term absentees list, this winter provides an opportunity for a host of Klopp’s fringe figures, and Naby Keita, Adam Lallana and Xherdan Shaqiri are among those on the bench this afternoon.
After a disappointing 1-1 draw in midweek, the visit of Brighton is a chance to return to winning ways, and Anfield will be hoping for a more convincing display this time out.
Liverpool: Alisson; Alexander-Arnold, Lovren, Van Dijk, Robertson; Wijnaldum, Henderson, Oxlade-Chamberlain; Salah, Mane, Firmino
Substitutes: Adrian, Gomez, Milner, Keita, Lallana, Shaqiri, Origi
Brighton: Ryan; Montoya, Webster, Dunk, Burn; Gross, Stephens, Propper, Bissouma, Mooy; Connolly
Substitutes: Button, Duffy, Scheletto, Alzate, Trossard, Maupay, Murray