Thiago returned to training on Boxing Day, following eight days out having tested positive for COVID-19 at Kirkby on December 18.
It left the Spaniard to spend Christmas Day alone, away from his wife and two children, before being reunited on December 26 to celebrate.
His time at home was interrupted, however, by another trip to Liverpool’s training ground, with Klopp holding a session ahead of the clash with Leicester.
Thiago was involved with the group that day, but 48 hours later he was omitted from the squad at the King Power, while Virgil van Dijk and Fabinho, along with substitute Curtis Jones, returned after isolation.
And speaking to Amazon Prime Video ahead of kickoff, Klopp explained that his No. 6 had felt the effects of his time away from training and had to be omitted.
“Thiago was in training one day, actually, and the next day he felt a little bit here and there,” he said.
“So we just had to leave him at home.”
Liverpool were also without an unnamed young player due to a positive Covid test, and despite Klopp’s call for “transparency” with cases in the Premier League, his identity remains unknown.
Fingers will remain crossed that Minamino and Divock Origi can return to fitness as soon as possible, with Mohamed Salah and Sadio Mane due to depart for the Africa Cup of Nations after the Chelsea game.